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March 14, 2016 By NootropicSupplements

Pyritinol Nootropic Supplements Review – Fuel To Your Brain?

Pyritinol Nootropic Supplements Review – Fuel To Your Brain?

Pyritinol is a supplement that belongs to class cholinergic nootropic. It has been associated with enhanced cognitive function and emotional state. It is viewed as a semi-natural and semi-synthetic chemical substance as it is synthesized in a research laboratory with several natural substances.

The natural chemical compounds consist of Vitamin B6, which is one of the most essential nutrients for the body. Pyritinol is basically two Vitamin B6 molecules, that are joined together. This provides Pyritinol the same benefits to Vitamin B6.

You can acquire Vitamin B6 the natural way from a variety of foods such as chickpeas, fish, chicken and potatoes. When the human brain contains an adequate amount of Vitamin B6, it can effectively create numerous neurotransmitters that are vital to the functionality of the brain. Pyritinol uses all the benefits of Vitamin B6 and then enhances them to provide powerful effects on the focus, memory and mood.

pyritinol

How Does Pyritinol Work?

Pyritinol is a unique nootropic cholinergic in its class. The same as with all the other cholinergics, Pyritinol boosts the learning capabilities and memory retention by increasing the levels of acetylcholine in the brain.

After Pyritinol crosses the blood-brain barrier, it targets the central nervous system, which then enhances the utilization of glucose and increases the levels of dopamine in the brain. This is exactly what makes Pyritinol unique. Dopamine is the feel good neurotransmitter of the body system, and increasing its levels can greatly improve your state of mind.

Why does it transpire? Because, Pyritinol is a precursor of dopamine. When you take Pyritinol, it increases the levels of dopamine and provides the feeling of satisfaction. The impact is a lot like an anti-depression medication. Higher levels of dopamine will allow you to feel more inspired and more focused.

Another important mechanism of Pyritinol is its neuroprotectivity. Pyritinol can be used to cure hangovers because it boosts the neuroprotection in the brain, which lessens the degradation of brain cells and neurotransmitters. Therefore, when you have plenty of alcohol consumption, the brain does not take the same beating as it normally would if you did not use Pyritinol. While some people use Vitamin B6 to cure their hangovers, Pyritinol provides the same fighting benefits for hangover.

History of Pyritinol

In 1961, Pyritinol was synthetized by a Merck Laboratories, which is a pharmaceutical firm. Merck Laboratories simply combined two Vitamin B6 molecules together.

Unlike some other nootropic supplements, Pyritinol has been recognized to be used as a medical treatment in many countries in the world. Many medical professionals in European countries use Pyritinol for treatment of individuals with chronic degenerative brain problems, including dementia. Portugal, Germany, Greece, Austria, France and  Italy are some of the countries where it is approved for treatment.

After many years of research, it was introduced in the market in the 1970s, in which it was utilized for clinical applications like for the treatment of stroke patients and people with Alzheimer’s disease. In the 1990s, it has been offered as a nootropic health supplement in America and various other countries.

Additional research studies have showed that Pyritinol can be used as to help improve mood, to cure hangover and to treat arthritis.

France has also approved the usage of Pyritinol, but only as a cure for rheumatism. It is not currently approved for usage particularly in the United Kingdom, but it is available in many other countries. You can buy Pyritinol on the internet or in over the counter drug stores. Approximately 100,000 individuals have been using Pyritinol in the EU within the last five years, which makes it one of the most widely used nootropic supplements available on the market today.

A lot of extensive studies about Pyritinol has been conducted in both clinical and scientific settings through the years. A particular study in 1990 involved a small group of 12 individuals who were given Pyritinol in a short time period. Those participants exhibited a noticeable difference especially in reaction time tests, but not on memory tests.

nootropic-Pyritinol

Tips To Using Pyritinol

Pyritinol is commonly used as a tablet or capsule, although you can find certain Pyritinol in powder form on the web. In any case, the suggested daily dosage of Pyritinol is 400 mg to 600 mg that is split into two. As an example, some people usually take 300 mg in the morning and another one during lunch time, as a way to increase the cognitive performance in the normal working hours.

If you are a beginner in using Pyritinol, the recommended daily dosage starts with two 100 mg every day. By doing this, your system can grow accustomed to its effects. On the other hand, more experienced users consume up to 1,600 mg regularly, split into two dosages. Many users claim to experience positive effects upon consuming Pyritinol with meals, that could possibly help in absorption and digestion. Even so, you are able to take it with or without a meal.

Specialists recommend cycling Pyritinol on and off The same as with a lot of nootropic supplements, you can build a tolerance to Pyritinol when getting it for long periods of time. Some users cycle their dosages over the course of the week, consuming small amounts on Monday, larger dosagesfor the next three days, and then a small dosage on Friday. Other people cycle it on and off by a few weeks at a time. Consuming it for one week and then cycling it off it for the next two weeks as a way to lessen the tolerance.

Benefits Of Pyritinol

Pyritinol is regarded as one of the most effective cholinergics available today due to its  wide array of impressive benefits including the following below:

  • Better Mental Energy – Pyritinol increases the glucose metabolism of the brain. Soon after crossing the blood-brain barrier, it improves glucose metabolic rate, making your brain easily access the nutrients and oxygen it requires from the blood vessels. It can significantly develop your mental energy.
  • Increased Neuroprotection – Pyritinol works as an antioxidant and increasing neuroprotectivity at the same time. This means there are lesser toxins in the brain. This also indicates that the neurotransmitters and brain cells can withstand damage faster and easier. This is why many people take Pyritinol to cure hangover or as a preventative measure.
  • Better Memory – Just like any cholinergic, Pyritinol improves the ability of the brain to create new memories and store them for future use. However, Pyritinol is not nearly as potent compared to other cholinergics in terms of memory recall. Therefore, if this is the benefit you are interested in the most, it is suggested to use another cholinergic supplement such as Citicoline or Alpha GPC.
  • Improved Concentration And Focus – The same procedure that provides you with improved mental energy can also improve your concentration and focus. Oftentimes, the brain begins to wander since it is unable to acquire the nutrients and oxygen that it needs to concentrate on a task. Pyritinol increases the capability of the blood to give fuel to the brain.
  • Minimized Stress And Anxiety – Pyritinol, which contains Vitamin B6, is a dopamine precursor. Dopamine is referred to as a feel good  hormone. The body naturally produces dopamine especially when you eat good food. Pyritinol helps to reduce stress and anxiety while it improves your mood.

Pyritinol Side Effects

The Pyritinol has very rare side effects, although they do happen. As stated earlier, Pyritinol is a popular pharmaceutical item in Europe. And so, it has a long history of usage and its negative effects have been carefully documented through the years.

Diarrhea, fatigue, rashes, nausea, headaches, irritability and insomnia are some of the side effects that some users have reported experiencing while taking Pyritinol. Some of these adverse reactions have been linked to allergic reactions in the substance. If you are concerned about these negative effects, consult with a doctor. Generally speaking, you should talk to a healthcare professional before you take Pyritinol or any nootropic supplement.

There is one major side effect that is reported from using Pyritinol; a certain report involved a person acquiring pancreatitis after consuming 600 mg for over three months every day. While it is a rare incident, it indicates that cycling a great idea. There were also some reports of acquiring acute hepatitis after taking it for an extended time period with consistent dosage.

Buying Pyritinol Supplements Online

When you purchase Pyritinol on the internet or in drugstores, you will likely come across one of three nootropic brands. Presently, Pyritinol is only manufactured by two firms in the world. Some popular brand names include Renervol, Encephabol and Ence. Two of them are developed by Merck, and the other one is manufactured by K. C. Laboratories.

Purchasing Pyritinol via online is a lot easier than ever before, as they are discrete, convenient and affordable. Pyritinol is also available over the counter in most European countries. But, it must be bought via the internet in the UK. It is also available in America and is generally legal in most of the world. Overall, you will not need a prescription to be able to buy Pyritinol online.

Filed Under: Nootropic Types

March 11, 2016 By NootropicSupplements

Noopept Nootropic Supplements Review – Brain Activator?

Noopept Nootropic Supplements Review – Brain Activator?

One of the most popular nootropic drugs in the market today is Noopept, a racetam-like drug in terms of its effects but is considered to be a peptide. If you’re thinking of taking this smart drug, read on.

The Peptide Power of Noopept

Peptide smart drugs have numerous advantages over the other types of nootropics. One of the most important, according to so many experts, is its bioavailability. This basically means that the drug is absorbed very quickly in the bloodstream, allowing it to cross the blood-brain barrier faster. Based on test, the bioavailability of Noopept is a thousand times better than Piracetam, another nootropic in the market.

noopept

The Direct Effects of Noopept to the Brain 

Like other nootropic, this drug boosts the growth of neurons and, consequently, improves one’s memory prowess. This means that users can learn faster and recall information better even at a later date.

It also has neuro-protective properties which can aid in immense focus and concentration. It is also said to relieve stress and anxiety, minimize irritability and help with various types of sleep disorders.

A Short History of Noopept

Developed by JSC LEKKO in the Soviet Union during that Cold War back in the 70s, Noopept was prescribed by so many doctors in Russia and in neighboring states for treating stress, anxiety and even degenerative brain diseases and conditions. This is still being prescribed and used up to this day.

It was only twenty years ago, in 1995, when it was patented in the United States. It was at that time too when smart drugs were gaining recognition in the country. But unlike in Russia, Noopept can be bought in the US over the counter as a nutritional supplement and not as a prescription drug.

Important Note Here!

Noopept has not been tested by either the European Medicines Agency or the US’ FDA – and this is because it’s a nutritional supplement and not a medication. It is important to note, also, that this is the case for most smart drugs in the market today.

The Function of Noopept in the Body 

noopept-reviewRemember what we have mentioned early on in the article: Noopept acts like racetams but is not one. This is because it targets Acetylcholine, specifically the AMPA and NDMA receptors to allow the easier absorption of information by neurotransmitters. All those actions, in turn, aids in sharper focus and clearer cognitive capacity.

But this is where the difference between Noopept and other racetams lies: the glutamate transmission of the drug to the brain. This smart drug prevents glutamate breakdown which is critical to various cognitive processes including memory, learning, and intelligence.

Aside from that, it also enhances the metabolism of glucose. This means that oxygen, as well as vitamins and a bevy of other nutrients, are absorbed more easily through the bloodstream and into the brain. Mental focus and clarity is also made better because with improved glucose absorption and metabolism comes a boost of energy.

Noopept is absorbed via the GIT or the gastrointestinal tract which means that the effects of the drug will be faster than usual.

The Other Benefits of Noopept

While the main benefits of this smart drug has been mentioned above, here are more specific ones which we would like to enumerate:

Improved Memory 

It increases one’s ability to learn, specifically in processin new information, and then recall that information even at a later date.

Boosts Mental Energy 

We have all felt mental fatigue at certain times, inhibiting our ability to work on important tasks. But because Noopept can enhance our mental energy by improving focus and attention span, we can work on whatever it is that we need to do without getting tired.

Brain Detoxification and Better Nerve Development 

As a neuro-protectant, Noopept kills various toxins like free radicals in the brain. Because of that, nerves, neurotransmitters and neurons are healthier which – in turn – improves the overall function of the brain.

Better Brain Communication 

Because Noopept improves the function of AMPA and NDMA receptors, the communication between synaptic pathways and neurons in the corpus callosum (the bridge connecting the right and left hemispheres of the brain) are greatly improved.

Repairing Damaged Neurons 

Brain cells, just like anything in this world, undergo wear and tear. But this normal occurrence is reduced with the use of Noopept as evidenced in a study made with lab rats several years ago. This means that degenerative diseases like Alzheimer’s can be dealt with effectively using this drug.

Using Noopept Properly      

Because this is a very powerful drug, it must be taken in small doses only. The recommended dosage is noted on the product labels.

First of all, Noopept must not be taken in with other nootropics, whether that’s a racetam or a peptide. It’s also best not to take this with any other brain supplements, specifically Choline-based ones. Alpha GPC and Citicoline are two of those Choline supplements which can cause bad headaches with Noopept.

Like any other drugs (medications or supplements), it is best that you talk with your doctor before you include Noopept in your diet. If you have heart and / or liver conditions, it is best that you don’t use this or any other nootropics. Pregnant women should not take this either.

There are various ways on how Noopept can be taken. Some mix the powder with water. Others take it sublingually (placing it under the tongue) for stronger bioavailability and faster effectiveness.

But according to experts, it is best for beginners to start with 5 mg of Noopept, taken three times a day. Increasing the dosage over time to a total of 10 mg a day is good enough although 30 mg is not too much either.

Manufacturers do warn not to go over 60mg over the course of a day since too much stimulation of Glutamate receptors is disadvantageous. Then there’s the possibility of increased side effects.

The Possible Side Effects of Noopept

Fatigue, headaches, nausea and insomnia are some of the common side effects of this nootropics. However, these are only experienced when too much of it is taken in per day.

As mentioned, this is safe to use because it has very low toxicity. After undergoing several clinical trials, Noopept is proven to be a safe supplement – as long as the recommended daily dosage is followed (for beginners) before one starts to increase it to the maximum that is 30 mg.

Noopept Available Online

While there are numerous shops (retail drug stores) which have Noopept available, your best option would be to order this on the internet. Besides the fact that it would be easier to find it online, it’s cheaper also. With fast shipping offered these days, you will have a bottle in your front door within 24 hours. So order now!

Filed Under: Nootropic Types

February 16, 2016 By NootropicSupplements

Modafinil Nootropic Supplements Review: All About Modafinil

Modafinil Nootropic Supplements Review: All About Modafinil

One of the most popular smart drug prescriptions today, designed to increase focus and boost energy, is Modafinil (Provigil). It is given to people who find it hard to sleep, usually. But it has been prescribed, too, to those who need increased concentration for working and / or studying.

Modafinil: A Popular Smart Drugs

Officially, this is a prescription drug given only to those with sleep apnea and narcolepsy. And doctors are very strict in writing a prescription for this.

However, those who want to take this in as a smart drug can get it even without a prescription by buying certain brands (albeit slightly modified) online, including the following:

  • Provigil
  • Alertec
  • Modiodal
  • Modapro
  • Sun Pharma Modalert

A Short History of Modafinil

This was developed in the 1970s by Michel Jouvet, a French professor. A decade and so later in 1986, it underwent clinical testing as an experimental drug to treat narcolepsy. As it proved to be effective, it has entered the commercial pharmaceutical market pretty quickly.

Cephalon, a biopharmaceutical group in the USA which started in 1987, has started to commercialize this. As one of the biggest global pharma companies, they now own the intellectual property right to Modafinil brand name Provigil.

While Modafinil still is the number one option for those who have narcolepsy and / or sleep apnea, it has been used by so many for focusing and staying alert for long periods of time such as night shift workers and even soldiers.

Cephalon has been throwing lawsuits here and there, defending their patent and intellectual property rights since there have been numerous companies making different versions of Modafinil.

For instance, this smart drug is widely marketed as Alertec online, primarily in Canada and the USA. This is a cheaper version of Provigil, even if both make use of the same formulas. Despite the aggressive ‘manhunt’ for Modafinil brands, there are still other ‘generic’ versions of Modafinil too, especially if you look hard enough.

smart-brain-drugs

The Functionality of Modafinil

The main target of Modafinil is the PSS or Peripheral Sympathetic System. The Anterior hypothalamus nucleus, that which regulates our sleep cycle, is the main area in the brain that is affected by the drug.

There have been theories that it also affects the CNS or Central Nervous System, although the function has not been studied yet to be fully appreciated.

There have been several speculations as to how this wonder smart drug functions in the brain. One of these is that Modafinil boosts Anandamine, a neurotransmitter which works with the Anterior hypothalamus nucleus to regulate sleep.

Apparently, increased Anandamine can also increase dopamine – the neurotransmitter regulating mood, cognitive ability, and motor functions, among so many others. It also has the ability of increasing glutamate in the brain by decreasing GABA.

There is another interesting function of Modafinil when taken: increased histamine activity.  This is said to be caused by Modafinil, the name of the active ingredient of the same drug.

Last but not the least, this sleep-regulator / smart drug has a direct effect on orexins, the peptides of the brain. When activated, both histamine and dopamine levels are increased helping both insomniacs and narcoleptics with their sleep patterns.

The Amazing Benefits of Modafinil 

Aside from its primary effect, that with helping those with sleep disorders regulate their sleep cycles better, Modafinil has numerous cognitive benefits too.

It is quite unique as a smart drug, lasting longer than other nootropics in the market and is multifunctional in the sense that it affects several parts of the brain. But below are its main advantages:

Mood Improvement 

Those who have used Modafinil have said that their moods have been lifted with continued use. This could be because of the increase in Dopamine in the brain.

Long Hours of Wakefulness 

Remember that this is a drug for treating narcolepsy. So those not suffering from that sleep condition can expect that they will be awake for at least 10 to even 12 hours a day. It is very important, therefore, to take the drug early in the morning and not at night, especially if you want to sleep well.

Amazing Focus and Concentration 

Modafinil basically works like caffeine in helping one focus. With its effect of wakefulness, it helps a great deal in making one very productive with whatever it is that they do.

Cognitive Function Enhanced and Retained 

It has been said earlier that Modafinil increases cognitive functionality, helping improve logical thinking. While this could be because of the increase in dopamine and glutamate levels in the brain, this effect of Modafinil still needs to undergo research and testing to be better understood.

Regulated Sleep 

Modafinil is prescribed mainly to those with insomnia, narcolepsy and other sleep disorders. If you are having troubles sleeping, you could ask your doctor for this drug.

The Right Usage of Modafinil

This is taken orally, either on a full or empty stomach. Doctors suggest that this be taken in the morning as it provides that 10-12 hours straight wakefulness. Taking it mid-day would make it hard for people to sleep at night already.

However, if you need to be up at night (for students doing school projects or employees given night shifts), then it is best that you take the medication an hour before your shift.

The recommended daily dosage of Modafinil, especially for beginners, is very low. Even so, you will feel the effects already without suffering from the common side effects of the drug. Most of the time, 200 mg of Modafinil is prescribed by doctors for daily use. This will last for 12-15 hours already.

Those who are cycling the drug should adjust the dosage for the week. To avoid tolerance development to Modafinil, take a 100mg early during the week and increase it bit by bit to 200mg by week’s end.

It is strongly recommended to follow the directions on the product label when planning to take Modafinil. It is also best to ask your doctor if you can use Modafinil or any other nootropic medications for that matter, especially if you have health conditions or are already taking in certain medications.

Modafinil-brain-health

The Side Effects of Modafinil

Most of the side effects of Modafinil, which aren’t serious to begin with, are the same with other nootropics in the market today. These mild symptoms include the following:

  • Nausea
  • Headaches
  • Lack of Appetite
  • Nervousness
  • Hypertension

In fact, if the directions for use are followed well, these won’t be a problem at all. As of the moment, there are no reports yet about dangerous effects of the drug, making this a pretty safe medication.

Important Note Here:

While this is a very good nootropic and is proven very effective for sleep disorders, it is not the right drug for everyone. Because it has mild stimulants (like caffeine, as aforementioned), it is not good for those with heart and liver conditions, high blood pressure, and pre-existing mental health problems. Again, it would be best to consult with an expert before you start taking this in.

Modafinil Available Online?

While this is available in retail drug stores, one would not be given Modafinil if a prescription is not presented. But other brands which are considered as ‘supplements’ more than medications, such as Provigil and Alertec, are available on the internet even without doctor’s prescription.

Filed Under: Cognitive Power, Nootropic Types

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